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Preparation of ibuprofen/lipid composite microparticles by supercritical fluid technique

WANG Xia, CHEN Hui, GUO Yanni, SU Yuzhong, WANG Hongtao, LI Jun

Frontiers of Chemical Science and Engineering 2008, Volume 2, Issue 4,   Pages 361-367 doi: 10.1007/s11705-008-0066-4

Abstract: Using the CO- and N-assisted atomization processes, the production of ibuprofen/lipid composite microparticles is investigated, in which the lipid includes myristic acid and tripalmitin. The produced composite particles show similar morphology to that of the pure lipids obtained by the same process. In the case of the N-assisted process, the average size of composite particles is slightly larger than that of the pure lipid particles due to the difficulty of solidification when using N. In the case of the CO-assisted process, the average size of composite particles is slightly smaller than that of the pure myristic acid particles, but slightly larger than that of the pure tripalmitin particles. The dissolution study reveals that the drug release from the ibuprofen/myristic acid particles is enhanced in comparison with that of the unprocessed ibuprofen. For the particles produced by the N-assisted process, the X-ray diffraction (XRD) patterns clearly indicate the encapsulation of ibuprofen into myristic acid. The obtained ibuprofen/tripalmitin composite particles with 5% or 20% of ibuprofen (in mass) evidently show the controlled drug release: only about 20% of the drug is released in 500 min from the ibuprofen/tripalmitin composite particles consisting of 20% ibuprofen prepared by the CO-assisted process, and the same release is obtained from the ibuprofen/tripalmitin composite particles containing 5% ibuprofen prepared by the N-assisted process.
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Recovery of rare and precious metals from urban mines—A review

Mengmeng Wang, Quanyin Tan, Joseph F. Chiang, Jinhui Li

Frontiers of Environmental Science & Engineering 2017, Volume 11, Issue 5, doi: 10.1007/s11783-017-0963-1

Abstract: pyrometallurgical, hydrometallurgical, and biometallurgical processing), and emerging (electrochemical, supercriticalfluid, mechanochemical, and ionic liquids processing) technologies.Newly developed technologies—electrochemical, supercritical fluid, ionic liquid, and mechanochemical—have

Keywords： Rare and precious metals (RPMs)     Distribution characteristics     Recycling technology     Emerging technology     Supercriticalfluid    

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Technologies for extracting lipids from oleaginous microorganisms for biodiesel production

Cunwen WANG, Lu CHEN, Bajpai RAKESH, Yuanhang QIN, Renliang LV

Frontiers in Energy 2012, Volume 6, Issue 3,   Pages 266-274 doi: 10.1007/s11708-012-0193-y

Abstract: Recently, biodiesel has received much more attention. Soybean oil, rapeseed oil, palm oil and corn oil are primary feedstock for biodiesel production. However, biodiesel production from these traditional oil-rich crops is limited by land availability, climate, and environmental and social issues regarding the use of feed and food crops for fuel. Oleaginous microorganisms, including microalgae, bacteria, yeast and fungi can be cultivated with high lipid contents and used as promising feedstock for biodiesel production. However, the high cost of biodiesel production using oil microorganisms has been the biggest obstacle for its industrialization. The process of biodiesel production from microorganisms involves many steps, of which the lipids extraction is the most important and costly. Therefore, searching for an effective and economical extraction system is critical. Various approaches of lipids extraction are discussed in this review, including traditional extraction procedures such as solvent extraction, pressing and solvent integrated extraction, as well as some new procedures.

Keywords： microorganisms     biodiesel     solvent extraction     ultrasound-assisted extraction     microwave-assisted extraction     supercriticalfluid extraction (SFE)    

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Calculation and analysis of sub/supercritical methanol preheating tube for continuous production of biodieselvia supercritical methanol transesterification

Wen CHEN, Weiyong YING, Cunwen WANG, Weiguo WANG, Yuanxin WU, Junfeng ZHANG,

Frontiers in Energy 2009, Volume 3, Issue 4,   Pages 423-431 doi: 10.1007/s11708-009-0075-0

Abstract: Supercritical methanol transesterification for biodiesel has recently been concerned because of its obviousThe tubular reactor is an ideal reactor for continuous preparation of biodiesel via supercritical methanolmethanol preheating tube is necessary for the tubular reaction system because the reaction temperature for supercritical;600K, changes of the density, isobaric capacity, viscosity and thermal conductivity of sub/supercriticalthe basis of these thermophysical properties, an integration method is adopted for the design of sub/supercritical

Keywords： sub/supercritical methanol     preheating tube     integration method     biodiesel    

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A review on catalytic & non-catalytic bio-oil upgrading in supercritical fluids

Sainab Omar, Yang Yang, Jiawei Wang

Frontiers of Chemical Science and Engineering 2021, Volume 15, Issue 1,   Pages 4-17 doi: 10.1007/s11705-020-1933-x

Abstract: summarizes the key published research on the topic of bio-oil upgrading using catalytic and non-catalytic supercriticalfluid (SCF) conditions.have opted for non-precious metal catalysts such as acidic HZSM-5 which can promote esterification in supercriticalSupercritical methanol, ethanol, and water are most commonly used and demonstrate catalyst like activities

Keywords： bio-oil     upgrading     supercritical     review    

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Polydimethylsiloxane assisted supercritical CO

Weixia Wang, Shuai Zhou, Zhong Xin, Yaoqi Shi, Shicheng Zhao

Frontiers of Chemical Science and Engineering 2016, Volume 10, Issue 3,   Pages 396-404 doi: 10.1007/s11705-016-1577-z

Abstract: The effect of PDMS viscosity on the foaming behavior of HMSPP was systematically investigated using supercritical

Keywords： high melt strength polypropylene (HMSPP)     polydimethylsiloxane (PDMS)     supercritical CO2     foaming    

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Corrosion mechanisms of candidate structural materials for supercritical water-cooled reactor

Lefu ZHANG, Fawen ZHU, Rui TANG

Frontiers in Energy 2009, Volume 3, Issue 2,   Pages 233-240 doi: 10.1007/s11708-009-0024-y

Abstract: strengthened steel are presently considered to be the candidate structural or fuel-cladding materials for supercriticalthose candidate materials exhibits quite complicated mechanism in high-temperature and high-pressure supercritical

Keywords： supercritical water-cooled reactor     general corrosion     oxide film     corrosion mechanism    

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Development of a supercritical and an ultra-supercritical circulating fluidized bed boiler

Junfu LYU, Hairui YANG, Wen LING, Li NIE, Guangxi YUE, Ruixin LI, Ying CHEN, Shilong WANG

Frontiers in Energy 2019, Volume 13, Issue 1,   Pages 114-119 doi: 10.1007/s11708-017-0512-4

Abstract: The supercritical circulating fluidized bed (CFB) boiler, which combines the advantages of CFB combustionwith low cost emission control and supercritical steam cycle with high efficiency of coal energy, isDifferent from the supercritical pulverized coal boiler that has been developed more than 50 years, thesupercritical CFB boiler is still a new one which requires further investigation.The design theory and key technology for supercritical CFB boiler were proposed.

Keywords： supercritical     circulating fluidized bed boiler     development     demonstration    

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Thermo-economic analysis of a direct supercritical CO electric power generation system using geothermal

Frontiers in Energy 2022, Volume 16, Issue 2,   Pages 246-262 doi: 10.1007/s11708-021-0749-9

Abstract: A comprehensive thermo-economic model combining a geothermal heat mining system and a direct supercritical

Keywords： geothermal heat mining     supercritical CO2     power generation     thermo-economic analysis     optimization    

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Production of renewable fuels by blending bio-oil with alcohols and upgrading under supercritical conditions

Sainab Omar, Suzanne Alsamaq, Yang Yang, Jiawei Wang

Frontiers of Chemical Science and Engineering 2019, Volume 13, Issue 4,   Pages 702-717 doi: 10.1007/s11705-019-1861-9

Abstract: The work studied a non-catalytic upgrading of fast pyrolysis bio-oil by blending under supercriticalThe GCMS analysis indicated that the supercritical methanol reaction removed the acids in the bio-oilconsequently the pH increased from 2.39 in the crude bio-oil to 4.04 after the supercritical methanolThe ester contents increased by 87.49% after the supercritical methanol reaction indicating ester formationAfter the supercritical isopropanol reaction, the heating value of the liquid product slightly further

Keywords： bio-oil     blending     supercritical     upgrading     characterisation    

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Updating the Fossil-fired Power Infrastructure via Supercritical Thermal Power Units

Song Zhiping

Strategic Study of CAE 2002, Volume 4, Issue 2,   Pages 22-27

Abstract: Numerous efforts have been made worldwide to reach high levels of efficiency by using super-and ultra supercritical

Keywords： thermal power infrastructure     supercritical steam conditions     ultra-supercritical power unit     sustainable    

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Micronization of curcumin with biodegradable polymer by supercritical anti-solvent using micro swirl

Kimthet Chhouk, Wahyudiono, Hideki Kanda, Shin-Ichro Kawasaki, Motonobu Goto

Frontiers of Chemical Science and Engineering 2018, Volume 12, Issue 1,   Pages 184-193 doi: 10.1007/s11705-017-1678-3

Abstract: swirl mixer was employed to produce the micronized curcumin with polyvinylpyrrolidone (PVP) by the supercritical

Keywords： micronization     curcumin     polyvinylpyrrolidone     supercritical anti-solvent     swirl mixer    

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Key problems and solutions in supercritical CO

Haizhu WANG, Gensheng LI, Bin ZHU, Kamy SEPEHRNOORI, Lujie SHI, Yong ZHENG, Xiaomei SHI

Frontiers in Energy 2019, Volume 13, Issue 4,   Pages 667-672 doi: 10.1007/s11708-019-0626-y

Abstract: Supercritical CO fracturing is considered to be a new method for efficient exploitation of unconventionalSupercritical CO has many special properties including low viscosity, high diffusion coefficient, andfast leak-off and high requirement for pump displacement, the displacement can be increased or the pad fluidAfter solving the above three problems, the field test of supercritical CO fracturing can be conductedThe research results can promote the industrialization process of supercritical CO fracturing.

Keywords： supercritical CO2     fracturing     friction loss     proppant carrying     flied test problem    

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A new heat transfer correlation for supercritical fluids

Yanhua YANG, Xu CHENG, Shanfang HUANG

Frontiers in Energy 2009, Volume 3, Issue 2,   Pages 226-232 doi: 10.1007/s11708-009-0022-0

Abstract: A new method of heat transfer prediction in supercritical fluids is presented.

Keywords： super critical fluids     heat transfer     circular tubes     prediction method    

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Review of the LNG intermediate fluid vaporizer and its heat transfer characteristics

Frontiers in Energy 2022, Volume 16, Issue 3,   Pages 429-444 doi: 10.1007/s11708-021-0747-y

Abstract: The intermediate fluid vaporizer (IFV), different from other liquefied natural gas (LNG) vaporizers,Moreover, studies on the fluid flow and heat transfer behaviors of the supercritical LNG inside the tubesand the condensation heat transfer of the intermediate fluid outside the tubes are summarized.

Keywords： intermediate fluid vaporizer     design of structure and intermediate fluid     condensation heat transfer    

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Title Author Date Type Operation

Preparation of ibuprofen/lipid composite microparticles by supercritical fluid technique

WANG Xia, CHEN Hui, GUO Yanni, SU Yuzhong, WANG Hongtao, LI Jun

Journal Article

Recovery of rare and precious metals from urban mines—A review

Mengmeng Wang, Quanyin Tan, Joseph F. Chiang, Jinhui Li

Journal Article

Technologies for extracting lipids from oleaginous microorganisms for biodiesel production

Cunwen WANG, Lu CHEN, Bajpai RAKESH, Yuanhang QIN, Renliang LV

Journal Article

Calculation and analysis of sub/supercritical methanol preheating tube for continuous production of biodieselvia supercritical methanol transesterification

Wen CHEN, Weiyong YING, Cunwen WANG, Weiguo WANG, Yuanxin WU, Junfeng ZHANG,

Journal Article

A review on catalytic & non-catalytic bio-oil upgrading in supercritical fluids

Sainab Omar, Yang Yang, Jiawei Wang

Journal Article

Polydimethylsiloxane assisted supercritical CO

Weixia Wang, Shuai Zhou, Zhong Xin, Yaoqi Shi, Shicheng Zhao

Journal Article

Corrosion mechanisms of candidate structural materials for supercritical water-cooled reactor

Lefu ZHANG, Fawen ZHU, Rui TANG

Journal Article

Development of a supercritical and an ultra-supercritical circulating fluidized bed boiler

Junfu LYU, Hairui YANG, Wen LING, Li NIE, Guangxi YUE, Ruixin LI, Ying CHEN, Shilong WANG

Journal Article

Thermo-economic analysis of a direct supercritical CO electric power generation system using geothermal

Journal Article

Production of renewable fuels by blending bio-oil with alcohols and upgrading under supercritical conditions

Sainab Omar, Suzanne Alsamaq, Yang Yang, Jiawei Wang

Journal Article

Updating the Fossil-fired Power Infrastructure via Supercritical Thermal Power Units

Song Zhiping

Journal Article

Micronization of curcumin with biodegradable polymer by supercritical anti-solvent using micro swirl

Kimthet Chhouk, Wahyudiono, Hideki Kanda, Shin-Ichro Kawasaki, Motonobu Goto

Journal Article

Key problems and solutions in supercritical CO

Haizhu WANG, Gensheng LI, Bin ZHU, Kamy SEPEHRNOORI, Lujie SHI, Yong ZHENG, Xiaomei SHI

Journal Article

A new heat transfer correlation for supercritical fluids

Yanhua YANG, Xu CHENG, Shanfang HUANG

Journal Article

Review of the LNG intermediate fluid vaporizer and its heat transfer characteristics

Journal Article